Substrate: STAT 3 (Transcription factor)
Seq-ID: P40763 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-74756   ERBB2_HUMAN
MINT-6764613   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein dimerization activity,
calcium ion binding,
hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity,
protein kinase binding,
transcription activator activity,
transcription factor binding,
sequence-specific DNA binding transcription factor activity		 plasma membrane,
cytoplasm,
nucleus		 interleukin-6-mediated signaling pathway,
eating behavior,
glucose homeostasis,
cellular component movement,
response to estradiol stimulus,
temperature homeostasis,
interspecies interaction between organisms,
JAK-STAT cascade involved in growth hormone signaling pathway,
sexual reproduction,
eye photoreceptor cell differentiation,
negative regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 691 EAFGKYCRPESQEHPEADPGS - 17525332
HTP
0.18
 - -
0.67
 --
Y 705 PEADPGSAAPYLKTKFICVTP - 9083098
LTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 11429593
LTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP JAK2 9582023
LTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 15592455
HTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 12244095
LTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 14551213
LTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP ALK 11850821
LTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 9305919
LTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 18083107
HTP
0.63
 STAT3 SH2 -
0.34
 1BG1 138.86%
T 714 PYLKTKFICVTPTTCSNTIDL - 18669648
HTP
0.16
 - -
0.21
 1BG1 20.55%
T 717 KTKFICVTPTTCSNTIDLPMS - 18669648
HTP
0.44
 - -
0.27
 --
S 727 TCSNTIDLPMSPRTLDSLMQF - 14551213
LTP
0.75
 - -
0.45
 --
S 727 TCSNTIDLPMSPRTLDSLMQF IRAK1 15465816
LTP
0.75
 - -
0.45
 --
S 727 TCSNTIDLPMSPRTLDSLMQF PKC_delta 16951338
LTP
0.75
 - -
0.45
 --
S 727 TCSNTIDLPMSPRTLDSLMQF - 18669648
HTP
0.75
 - -
0.45
 --

Substrate: STAT 3 (Transcription factor)
Seq-ID: P42227 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
protein dimerization activity,
calcium ion binding,
protein kinase binding,
transcription activator activity,
transcription factor binding,
sequence-specific DNA binding transcription factor activity,
signal transducer activity		 plasma membrane,
cytoplasm,
nucleus		 transcription from RNA polymerase II promoter,
eating behavior,
glucose homeostasis,
cytokine-mediated signaling pathway,
regulation of multicellular organism growth,
acute-phase response,
temperature homeostasis,
JAK-STAT cascade involved in growth hormone signaling pathway,
sexual reproduction,
positive regulation of transcription from RNA polymerase II promoter,
eye photoreceptor cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 705 PEADPGSAAPYLKTKFICVTP - 15465816
LTP
0.63
 - -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 15923602
LTP
0.63
 - -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 11278353
LTP
0.63
 - -
0.34
 1BG1 138.86%
Y 705 PEADPGSAAPYLKTKFICVTP - 9531474
LTP
0.63
 - -
0.34
 1BG1 138.86%
S 727 TCSNTIDLPMSPRTLDSLMQF - 7543024
LTP
0.75
 - -
0.45
 --

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